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NCBI: db=pubmed; Term=adrenal tumor
Updated: 6 days 16 hours ago

An unusual case of simultaneous left glomus vagale, jugulare and tympanicum tumor.

Sun, 02/18/2018 - 08:55
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An unusual case of simultaneous left glomus vagale, jugulare and tympanicum tumor.

Pan Afr Med J. 2017;26:241

Authors: Bellasri S, Hmidi M

PMID: 28690755 [PubMed - indexed for MEDLINE]

[Macro-adrenal adenoma masking micronodular adrenal hyperplasia in patients with ACTH-independent Cushing's syndrome and refractory hypokalaemia].

Sun, 02/18/2018 - 08:55
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[Macro-adrenal adenoma masking micronodular adrenal hyperplasia in patients with ACTH-independent Cushing's syndrome and refractory hypokalaemia].

Pan Afr Med J. 2017;26:230

Authors: Alaya W, Bouchahda H, Fradi A, Zantour B, Sfar MH

PMID: 28690744 [PubMed - indexed for MEDLINE]

18F-FDG Uptake in Benign Fibrous Histiocytoma of Adrenal Gland: A Potential Pitfall.

Sun, 02/18/2018 - 08:55
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18F-FDG Uptake in Benign Fibrous Histiocytoma of Adrenal Gland: A Potential Pitfall.

Clin Nucl Med. 2017 Aug;42(8):622-623

Authors: Tan TH, Lai CNB

Abstract
A 47-year-old man with newly diagnosed nasopharyngeal carcinoma underwent staging F-FDG PET/CT. Apart from showing increased FDG uptake in the primary site and locoregional nodal and liver metastases, an unusual site of intense FDG focus was demonstrated in the left adrenal gland. He underwent CT-guided biopsy, and the histopathologic diagnosis was benign fibrous histiocytoma.

PMID: 28632691 [PubMed - indexed for MEDLINE]

Rebiopsy of Histological Samples in Pretreated Non-small Cell Lung Cancer: Comparison Among Rebiopsy Procedures.

Sun, 02/18/2018 - 08:55
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Rebiopsy of Histological Samples in Pretreated Non-small Cell Lung Cancer: Comparison Among Rebiopsy Procedures.

In Vivo. 2017 May-Jun;31(3):475-479

Authors: Hata A, Katakami N, Nanjo S, Okuda C, Kaji R, Imai Y

Abstract
AIM: The aim of the present study was to compare successful rate, failure reasons, and complications among procedures of histological rebiopsy.
PATIENTS AND METHODS: We retrospectively reviewed medical records of histologically rebiopsied cases with non-small cell lung cancer.
RESULTS: One hundred and eleven histological rebiopsies were performed in: 86 (77%) lung; 11 (10%) lymph node; 5 (5%) pleura; 4 (4%) liver; 2 (2%) muscle; 2 (2%) adrenal gland; and 1 (1%) rib. Successful rate by computed tomography-guided biopsy (CTGB), transbronchial biopsy (TBB), and ultrasound-guided biopsy were 86% (48/56), 90% (28/31), and 100% (24/24), respectively. Reasons for rebiopsy failure by CTGB were no/insufficient malignant cells (n=5) and pneumothorax (n=3), and those by TBB were no/insufficient malignant cells (n=2) and bleeding (n=1). Severe complications (≥grade 3): one grade 3 pneumothorax and one grade 4 air embolization were observed in two (2%, 2/111) cases receiving CTGB.
CONCLUSION: Rebiopsy of histological samples can be highly successful and feasible by optimal procedural selection.

PMID: 28438882 [PubMed - indexed for MEDLINE]

Lipomatous tumours in adrenal gland: WHO updates and clinical implications.

Sun, 02/18/2018 - 08:55
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Lipomatous tumours in adrenal gland: WHO updates and clinical implications.

Endocr Relat Cancer. 2017 Mar;24(3):R65-R79

Authors: Lam AK

Abstract
Adrenal lipomatous tumour is a group of adrenal tumours with a significant component of adipose tissue. According to the current World Health Organization (WHO) classification of tumours of endocrine organs, adrenal myelolipoma is the only entity amongst the group of tumours being described. In the literature, other more recently documented adrenal lipomatous tumours included 24 lipomas, 32 teratomas and 16 angiomyolipomas. Rare fatty tumours of the adrenal gland comprised liposarcoma, hibernoma, adrenocortical tumours with fat component and rare adrenal tumours with fat component. Myelolipoma comprises approximately 3% of primary adrenal tumour. It is noted more commonly in females and in the right adrenal gland. Approximately 40 bilateral myelolipomas were reported. The tumour is most frequently recorded in patients between fifth and seventh decades of life. Adrenal lipomas are often seen in males and in the right adrenal gland. They were commonly noted in patients in the sixth decade of life. The diagnosis could only be possible on examination of the surgically removed specimen. Adrenal teratomas were more common in females and with a bimodal age distribution. Slightly over 60% of the patients with adrenal teratoma are symptomatic. Adrenal angiomyolipomas were often symptomatic, more common in females and in the fifth decades of life. To conclude, adrenal lipomatous tumour is uncommon. They are often benign and non-functional. It is important to recognize the features of this group of lipomatous tumours in the adrenal gland as they are being detected on increasing incidence as a result of the wide-spread use of modern imaging modalities.

PMID: 28143811 [PubMed - indexed for MEDLINE]

Targeting PI3K/mTOR signaling exerts potent antitumor activity in pheochromocytoma in vivo.

Sun, 02/18/2018 - 08:55
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Targeting PI3K/mTOR signaling exerts potent antitumor activity in pheochromocytoma in vivo.

Endocr Relat Cancer. 2017 Jan;24(1):1-15

Authors: Lee M, Minaskan N, Wiedemann T, Irmler M, Beckers J, Yousefi BH, Kaissis G, Braren R, Laitinen I, Pellegata NS

Abstract
Pheochromocytomas (PCCs) are mostly benign tumors, amenable to complete surgical resection. However, 10-17% of cases can become malignant, and once metastasized, there is no curative treatment for this disease. Given the need to identify the effective therapeutic approaches for PCC, we evaluated the antitumor potential of the dual-PI3K/mTOR inhibitor BEZ235 against these tumors. We employed an in vivo model of endogenous PCCs (MENX mutant rats), which closely recapitulate the human tumors. Mutant rats with PCCs were treated with 2 doses of BEZ235 (20 and 30 mg/kg), or with placebo, for 2 weeks. Treatment with BEZ235 induced cytostatic and cytotoxic effects on rat PCCs, which could be appreciated by both staining the tumors ex vivo with appropriate markers and non-invasively by functional imaging (diffusion-weighted magnetic resonance imaging) in vivo Transcriptomic analyses of tumors from rats treated with BEZ235 or placebo-identified potential mediators of therapy response were performed. Slc6a2, encoding the norepinephrine transporter (NET), was downregulated in a dose-dependent manner by BEZ235 in rat PCCs. Moreover, BEZ235 reduced Slc6a2/NET expression in PCC cell lines (MPC) also. Studies of a BEZ235-resistant derivative of the MPC cell line confirmed that the reduction of NET expression associates with the response to the drug. Reduction of NET expression after BEZ235 treatment in vivo could be monitored by positron emission tomography (PET) using a tracer targeting NET. Altogether, here we demonstrate the efficacy of BEZ235 against PCC in vivo, and show that functional imaging can be employed to monitor the response of PCC to PI3K/mTOR inhibition therapy.

PMID: 27811202 [PubMed - indexed for MEDLINE]

Renal denervation attenuates aldosterone expression and associated cardiovascular pathophysiology in angiotensin II-induced hypertension.

Sun, 02/18/2018 - 08:55
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Renal denervation attenuates aldosterone expression and associated cardiovascular pathophysiology in angiotensin II-induced hypertension.

Oncotarget. 2016 Oct 18;7(42):67828-67840

Authors: Hong MN, Li XD, Chen DR, Ruan CC, Xu JZ, Chen J, Wu YJ, Ma Y, Zhu DL, Gao PJ

Abstract
The sympathetic nervous system interacts with the renin-angiotensin-aldosterone system (RAAS) contributing to cardiovascular diseases. In this study, we sought to determine if renal denervation (RDN) inhibits aldosterone expression and associated cardiovascular pathophysiological changes in angiotensin II (Ang II)-induced hypertension. Bilateral RDN or SHAM operation was performed before chronic 14-day Ang II subcutaneous infusion (200ng/kg/min) in male Sprague-Dawley rats. Bilateral RDN blunted Ang II-induced hypertension and ameliorated the mesenteric vascular dysfunction. Cardiovascular hypertrophy in response to Ang II was significantly attenuated by RDN as shown by histopathology and transthoracic echocardiography. Moreover, Ang II-induced vascular and myocardial inflammation and fibrosis were suppressed by RDN with concurrent decrease in fibronectin and collagen deposition, macrophage infiltration, and MCP-1 expression. Interestingly, RDN also inhibited Ang II-induced aldosterone expression in the plasma, kidney and heart. This was associated with the reduction of calcitonin gene-related peptide (CGRP) in the adrenal gland. Ang II promoted aldosterone secretion which was partly attenuated by CGRP in the adrenocortical cell line, suggesting a protective role of CGRP in this model. Activation of transforming growth factor-β (TGF-β)/Smad and mitogen-activated protein kinases (MAPKs) signaling pathway was both inhibited by RDN especially in the heart. These results suggest that the regulation of the renal sympathetic nerve in Ang II-induced hypertension and associated cardiovascular pathophysiological changes is likely mediated by aldosterone, with CGRP involvement.

PMID: 27661131 [PubMed - indexed for MEDLINE]

Alteration of sex hormone levels and steroidogenic pathway by several low molecular weight phthalates and their metabolites in male zebrafish (Danio rerio) and/or human adrenal cell (H295R) line.

Sun, 02/18/2018 - 08:55
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Alteration of sex hormone levels and steroidogenic pathway by several low molecular weight phthalates and their metabolites in male zebrafish (Danio rerio) and/or human adrenal cell (H295R) line.

J Hazard Mater. 2016 Dec 15;320:45-54

Authors: Sohn J, Kim S, Koschorreck J, Kho Y, Choi K

Abstract
Low molecular weight phthalates, such as diethyl phthalate (DEP), benzyl butyl phthalate (BBzP), or diisobutyl phthalate (DiBP), are suspected to disrupt endocrine system. However, their adverse effects on sex steroid hormones and underlying mechanisms are not well-documented. The aim of this study is to investigate the effects of major low molecular weight phthalates (LMWPs), i.e., DEP, BBzP, and DiBP, and their hydrolytic metabolites, on sex steroid hormone system, employing male zebrafish and/or a human adrenocortical carcinoma (H295R) cell. In male zebrafish, 14-day exposure to DEP, BBzP, or DiBP significantly decreased testosterone (T) concentrations. All test compounds significantly up-regulated cyp19a gene expression, and down-regulated star and 3β hsd genes in the male fish. In H295R cell, all test compounds except monoisobutyl phthalate (MiBP) reduced T concentrations and increased E2/T ratio. Gene expression changes in H295R cell, e.g., significant down-regulation of StAR gene and up-regulation of CYP19A gene, supported depressed synthesis of sex hormones in the adrenal cell. Our results show that not only DEP, BBzP, and DiBP, but also their hydrolytic metabolites disrupt sex hormone balances through modulating key steroidogenic genes in the human adrenal cells and in zebrafish.

PMID: 27513369 [PubMed - indexed for MEDLINE]

Cutaneous side effects caused by treatment for inflammatory bowel disease.

Sun, 02/18/2018 - 08:55
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Cutaneous side effects caused by treatment for inflammatory bowel disease.

Vojnosanit Pregl. 2016 Apr;73(4):382-9

Authors: Tarabar D, Kandolf-Sekulović L, Tatomirović Ž, Mijušković Ž, Milenković Z, Tarabar O, Pecelj-Broćić T

PMID: 29309107 [PubMed - indexed for MEDLINE]

Developing a Registry for Thyroid Incidentalomas: Lessons Learned and the Path Forward.

Sun, 02/18/2018 - 08:55
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Developing a Registry for Thyroid Incidentalomas: Lessons Learned and the Path Forward.

Thyroid. 2016 May;26(5):650-6

Authors: Davies L, Pichiotino E, Black WC, Tosteson AN

Abstract
BACKGROUND: Incidentalomas are findings on an imaging test done for other reasons, for which there are no matching symptoms in the patient. They are common in the adrenal gland, pancreas, liver, and thyroid, among other sites. Incidentalomas are a problem because we have a limited understanding of their natural history: it is difficult to know how much of a threat they pose to individual patients. An observational registry that would allow a systematic study of thyroid incidentalomas could reveal their natural history and the effect of detection on patients' lives, as well as document the cost to the healthcare system. A registry would help to determine which incidentalomas could be monitored and which require action.
STUDY DESIGN: A cohort study was conducted, with case identification via radiology imaging reports with follow-up through a minimum of one year post-identification.
RESULTS: In one year, >109,000 imaging studies were performed that might reveal an incidental thyroid finding (computed tomography scans of the neck or chest, magnetic resonance imaging of the neck, plain x-ray of the chest, non-thyroid directed ultrasound of the neck, positron emission tomography scan, or myocardial perfusion scan). A total of 125 patients were identified as having a thyroid nodule, with a <1% reporting rate among eligible imaging studies, much lower than other published estimates of incidental thyroid nodule prevalence on imaging. Of the 125 nodules, 46 had been previously identified (were not "new"). Of the 79 patients with new nodules, more than half (44; 53%) were not notified of the finding. The approved study design allowed contact only with those who had been clearly notified of their thyroid nodule. Among those who could be reached, many did not recall the finding (6/15; 40%). Of those who did recall the finding, none self-identified it as an incidentaloma.
CONCLUSIONS: There are serious logistical and ethical hurdles to developing observational registries of incidentalomas, as well as threats to data validity because incidentalomas are incompletely identified, reported, and acted upon. Solutions commonly used to optimize data quality for registries would increase reporting, but could potentially overwhelm the healthcare system and harm patients. A novel interventional design that is proposed here for future work may facilitate both study and amelioration of the problem.

PMID: 27028799 [PubMed - indexed for MEDLINE]

Medication Utilization and the Impact of Continued Corticosteroid Use on Patient-reported Outcomes in Older Patients with Inflammatory Bowel Disease.

Sun, 02/18/2018 - 08:55
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Medication Utilization and the Impact of Continued Corticosteroid Use on Patient-reported Outcomes in Older Patients with Inflammatory Bowel Disease.

Inflamm Bowel Dis. 2016 Jun;22(6):1435-41

Authors: Geisz M, Ha C, Kappelman MD, Martin CF, Chen W, Anton K, Sandler RS, Long MD

Abstract
BACKGROUND: Older individuals with inflammatory bowel disease (IBD) require ongoing medications. We aimed to describe (1) medication use in older and younger IBD patients and (2) medication associations with patient reported outcomes (PROs) in older patients.
METHODS: We conducted cross-sectional and longitudinal analyses within CCFA Partners internet-based cohort of patients with self-reported IBD. We assessed medication use by disease sub-type and age. We used bivariate analyses to (1) compare medication use in older and younger patients and (2) determine associations between continued steroid use and patient reported outcomes in older patients.
RESULTS: We included 5382 participants with IBD; 1004 were older (≥age 60). Older patients with Crohn's disease (CD) had lower antitumor necrosis factor alpha (anti-TNF) use at baseline (29.1% versus 44.3%, P < 0.001), comparable steroid use (16.0% versus 16.5%, P = 0.77), and higher aminosalicylate use (40.3% versus 33.9%, P = 0.003) versus younger patients. Older ulcerative colitis (UC) patients had similar anti-TNF use (16.0% versus 19.2%, P = 0.16), lower steroid use (9.6% versus 15.4%, P = 0.004), and higher aminosalicylate use (73.8% versus 68.2%, P = 0.04) at baseline. In longitudinal analyses, older CD patients had higher continued steroid use (11.6% versus 7.8%, P = 0.002); which was associated with worsened anxiety (P = 0.02), sleep (P = 0.01), and fatigue (P = 0.001) versus nonuse. Older CD patients on steroids, versus anti-TNF or immunomodulators, had increased depression (P = 0.04) and anxiety (P = 0.03).
CONCLUSIONS: Medication utilization differs in older patients with IBD. Older CD patients have higher continued steroid use associated with worsened patient reported outcomes. As in younger IBD populations, continued steroid use should be limited in older patients.

PMID: 26978725 [PubMed - indexed for MEDLINE]

adrenal tumor; +25 new citations

Sun, 02/11/2018 - 05:57

25 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results:

adrenal tumor

These pubmed results were generated on 2018/02/11

PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.

adrenal tumor; +28 new citations

Sun, 02/04/2018 - 02:58

28 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results:

adrenal tumor

These pubmed results were generated on 2018/02/04

PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.

Two cases of reversible male infertility due to congenital adrenal hyperplasia combined with testicular adrenal rest tumor.

Sun, 01/28/2018 - 00:10
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Two cases of reversible male infertility due to congenital adrenal hyperplasia combined with testicular adrenal rest tumor.

Reprod Med Biol. 2018 Jan;17(1):93-97

Authors: Tanaka M, Enatsu N, Chiba K, Fujisawa M

Abstract
Cases: Testicular adrenal rest tumor (TART) is one of the possible causes of male infertility, accompanied by congenital adrenal hyperplasia (CAH). Here are reported two cases of TARTs that were referred to Kobe City Medical Center West Hospital for the treatment of infertility and testicular tumors.
Outcome: In one case, the semen analysis was improved from oligoasthenozoospermia to normozoospermia after taking oral glucocorticoid supplementation. The other case of original azoospermia showed that sperm had ejaculated into the semen after taking oral glucocorticoid supplementation.
Conclusion: Although the prevalence of TARTs in male infertility is very rare, it is important to know how to approach this disease, considering the curable pathology of spermatogenesis and tumors resembling an appearance to germ cell tumors.

PMID: 29371828 [PubMed]

Development of new preclinical models to advance adrenocortical carcinoma research.

Sun, 01/28/2018 - 00:10
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Development of new preclinical models to advance adrenocortical carcinoma research.

Endocr Relat Cancer. 2018 Jan 25;:

Authors: Kiseljak-Vassiliades K, Zhang Y, Bagby S, Kar A, Pozdeyev N, Xu M, Gowan K, Sharma V, Raeburn CD, Albuja-Cruz M, Jones KL, Fishbein L, Schweppe R, Somerset HL, Pitts TM, Leong S, Wierman M

Abstract
Adrenocortical cancer (ACC) is an orphan malignancy that results in heterogeneous clinical phenotypes and molecular genotypes. There are no curative treatments for this deadly cancer with 35% survival at five years. Our understanding of the underlying pathobiology and our ability to test novel therapeutic targets has been limited due to the lack of preclinical models. Here, we report the establishment of two new ACC cell lines and corresponding patient derived xenograft (PDX) models. CU-ACC1 cell line and PDX were derived from a perinephric metastasis in a patient whose primary tumor secreted aldosterone. CU-ACC2 cell line and PDX were derived from a liver metastasis in a patient with Lynch syndrome. Short tandem repeat profiling confirmed consistent matches between human samples and models. Both exomic and RNA sequencing profiling were performed on the patient samples and the models, and hormonal secretion was evaluated in the new cell lines. RNA sequencing and immunohistochemistry confirmed expression of adrenal cortex markers in the PDXs and human tumors. The new cell lines replicate two of the known genetic models of ACC. CU-ACC1 cells had a mutation in CTNNB1 and secreted cortisol, but not aldosterone. CU-ACC2 cells had a TP53 mutation and loss of MSH2 consistent with the patient's known germline mutation causing Lynch syndrome. Both cell lines can be transfected and transduced with similar growth rates. These new preclinical models of ACC significantly advance the field by allowing investigation of underlying molecular mechanisms of ACC and the ability to test patient specific therapeutic targets.

PMID: 29371329 [PubMed - as supplied by publisher]

[A Case of Retroperitoneal Teratoma Difficult to Distinguish from Adrenal Tumor].

Sun, 01/28/2018 - 00:10
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[A Case of Retroperitoneal Teratoma Difficult to Distinguish from Adrenal Tumor].

Hinyokika Kiyo. 2017 Dec;63(12):525-528

Authors: Maenosono R, Saito K, Ibuki N, Takahara K, Inamoto T, Nomi H, Azuma H

Abstract
Retroperitoneal tumor is a rare tumor, with an incidence of 0.2 to 0.8%. Among such tumors, the frequency of teratomas ranges from 6 to 18%, and adult cases are extremely rare. We report a mature teratoma that occurred in the retroperitoneum of 43-year-old woman. She experienced back pain and a left adrenal gland mass was detected on computed tomography. Computed tomography and magnetic resonance imaging findings showed a cyst made of fat and calcification, but it was difficult to distinguish retroperitoneal teratoma from adrenal tumor in this case. The tumor was removed, and was mainly composed of a hair ball and fat. Pathological examination showed that the tumor was composed of stratified squamous epithelium, keratinizing component, cartilage, and bronchial epithelium, while no continuity with the adrenal gland was observed. Therefore, the tumor was diagnosed as a retroperitoneal teratoma.

PMID: 29370664 [PubMed - in process]

Case report: an identical twin with Sertoli-Leydig cell tumor.

Sun, 01/28/2018 - 00:10
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Case report: an identical twin with Sertoli-Leydig cell tumor.

Gynecol Endocrinol. 2018 Jan 24;:1-4

Authors: Cho K, Havelock JC, Gilks B, Dunne C

Abstract
Our report details the workup and management of a 43-year-old woman with an identical twin who presented with 2 years of virilization and secondary amenorrhea. Serum total testosterone was elevated. An MRI did not identify adnexal or adrenal pathology. Subsequent ovarian vein sampling demonstrated unilateral testosterone elevation. The patient underwent laparoscopic unilateral oophorectomy resulting in the diagnosis of Sertoli-Leydig cell tumor (SLCT). Although SLCT is a rare sex-cord ovarian tumor, it is associated with endometrial hyperplasia and malignancy. Our goals are to review the workup of androgen-secreting tumors and discuss the clinical importance of the DICER1 mutation in the context of SLCT. In this case, an identical twin underwent DICER1 testing which was one of the essential steps in her clinical management.

PMID: 29366348 [PubMed - as supplied by publisher]

Volumetric Modulated Arc (Radio) Therapy in Pets Treatment: The "La Cittadina Fondazione" Experience.

Sun, 01/28/2018 - 00:10
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Volumetric Modulated Arc (Radio) Therapy in Pets Treatment: The "La Cittadina Fondazione" Experience.

Cancers (Basel). 2018 Jan 24;10(2):

Authors: Dolera M, Malfassi L, Carrara N, Finesso S, Marcarini S, Mazza G, Pavesi S, Sala M, Urso G

Abstract
Volumetric Modulated Arc Therapy (VMAT) is a modern technique, widely used in human radiotherapy, which allows a high dose to be delivered to tumor volumes and low doses to the surrounding organs at risk (OAR). Veterinary clinics takes advantage of this feature due to the small target volumes and distances between the target and the OAR. Sparing the OAR permits dose escalation, and hypofractionation regimens reduce the number of treatment sessions with a simpler manageability in the veterinary field. Multimodal volumes definition is mandatory for the small volumes involved and a positioning device precisely reproducible with a setup confirmation is needed before each session for avoiding missing the target. Additionally, the elaborate treatment plan must pursue hard constraints and objectives, and its feasibility must be evaluated with a per patient quality control. The aim of this work is to report results with regard to brain meningiomas and gliomas, trigeminal nerve tumors, brachial plexus tumors, adrenal tumors with vascular invasion and rabbit thymomas, in comparison with literature to determine if VMAT is a safe and viable alternative to surgery or chemotherapy alone, or as an adjuvant therapy in pets.

PMID: 29364837 [PubMed]

Adrenal Collision Tumor Composed of Adrenocortical Adenoma and Pheochromocytoma.

Sun, 01/28/2018 - 00:10
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Adrenal Collision Tumor Composed of Adrenocortical Adenoma and Pheochromocytoma.

Chin Med J (Engl). 2018 Feb 05;131(3):374-375

Authors: Zhang CX, Tian Y

PMID: 29363662 [PubMed - in process]

Adrenal Vein Sampling Is the Preferred Method to Select Patients With Primary Aldosteronism for Adrenalectomy: Con Side of the Argument.

Sun, 01/28/2018 - 00:10
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Adrenal Vein Sampling Is the Preferred Method to Select Patients With Primary Aldosteronism for Adrenalectomy: Con Side of the Argument.

Hypertension. 2018 01;71(1):10-14

Authors: Deinum J, Prejbisz A, Lenders JWM, van der Wilt GJ

PMID: 29229748 [PubMed - indexed for MEDLINE]

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